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TOXINS
ON BOARD
By Diana Fairechild

DEAR
DIANA
"As
a flight attendant, I was exposed on to APU oil aboard an Airbus. Prior
to that, during a routine physical, my blood work was normal. After
my exposure, my blood showed elevated levels in my liver. I now suffer
from hypothyroidism. Two other flight attendants were also exposed and
are now experiencing similar health problems. Our employer, U.S. Airways,
has refused compensation for us."-JR
DEAR JR
I am sorry to hear about your health problems. Researchers now blame
chemical poisoning for many illnesses, though they go by a variety of
names including Gulf War Syndrome, Sick Building Sydrome, Multiple Chemical
Sensitivity (MCS), Environmental Illness, and Toxic Induced Loss of
Tolerance (TILT).
In addition,
neuro-degenerative diseases linked to toxins include lupus, multiple
sclerosis, Parkinson's, and lymphoma. Even Alzheimers apparently needs
an enviromental trigger.
Autoimmune
diseases such as rheumatoid arthritis and diabetes are also tracked
to toxins.
Here
is a narrative was written in 1991 by James M. Miller, M.D., as part of the
court record in my attempt to get Workers' Compensation from United Airlines
for poisoning her in my workplace, which I believe will be helpful to you
in understanding this problem.
----
"Humans,
like all living creatures, are by nature biochemical organisms. Our
continued good health is dependent upon the proper functioning of innumerable
enzymes participating in an enormous number of biochemical reactions.
"These reactions must take place at the proper time, at the proper
rate, to the proper extent. We see, smell, taste, hear, balance, walk,
talk, chew, swallow, reproduce, sleep, think, and remember as a result
of the proper functioning and proper balance of the many biochemical
processes that support these functions.
"Chemicals enter our bodies through the skin, the gastrointestinal
tract, and the respiratory tract. Certain substances are useful to the
body and support its biochemical mechanisms, while others are not useful
or are even harmful. The latter are called xenobiotics. We exercise
relatively little ability to be selective and tend to take in some of
all the chemical substances presented, whether they are desirable or
not.
"Once in the body, chemicals are distributed by the blood to all
organs. Chemical substances, which are not inert, have the capacity
to combine with the chemical substances of the tissues, forming new
compounds and altering the function of the tissue elements with which
they have combined.
"A xenobiotic that combines with an enzyme will alter the function
of that enzyme. As a result, the chemical reaction dependent upon that
enzyme may become too slow, ineffective, or perhaps not take place at
all. This would result in either a deficiency of some essential substance
or an accumulation of some intermediate substance, both of which are
harmful to the coordinated, balanced, physical/chemical mechanisms of
the body. Xenobiotics can combine with and alter the function of any
tissue component in the body, i.e., cell membranes, proteins, as well
as enzymes.
"We are fortunate in that we are endowed with an excess capacity
in all our organ systems. We have two kidneys but can survive on the
functional capacity of one normal kidney. We have two lungs but can
survive on just one.
"The capacity of most of our enzymes and biochemical processes
is greater than we usually require. Because of the excess capacity in
all our organ systems, we are able to sustain considerable injury and
diminution in functional capacity before there is any organ malfunction
and therefore any symptoms. Xenobiotic chemicals do their damage to
our body's chemical mechanisms one molecule at a time.
"Individuals exposed to xenobiotic chemicals on a regular basis
will experience regular injuries that will accumulate over time to eventually
result in organ malfunction.
"Whether or not one develops illness from chemicals depends upon
the extent of the injury caused by any given exposure, the rate at which
the injury can be repaired, and the frequency with which the exposure
and the injury are repeated.
"If
one goes to work and sustains an eight-hour exposure to a solvent, some
of the solvent will enter the body and combine with some of the tissue
components causing a finite amount of injury. This is true even though
the level of the solvent exposure may never have exceeded the OSHA standard
or any other standard that might be considered "safe." If
the injury can be completely healed in the sixteen off-duty hours, the
individual returns to work at 100% capacity and the situation is sustainable
indefinitely. If the extent of the injury is greater than can be repaired
in the sixteen off-duty hours, the individual returns to work at less
than 100% capacity.
"This sequence of events will be repeated each work day and the
individual will accumulate injuries, injuries which will eventually
lead to erosion of the excess functional capacity and organ malfunction.
This process will remain unnoticed until the loss of functional capacity
results in symptoms. At this point, the slightest increase in this dose
of the xenobiotic in question will provoke symptoms each and every time
it is encountered.
"There is a period of time when the injury is occurring but the
excess capacity has not yet been eroded away, so there are no symptoms.
There is another period where the extent of the damage results in symptoms
but the individual can still sustain life and might recover if the exposure
were to be terminated, although not necessarily without residual damage.
"There
is the final period where organ damage is irreversible and incompatible
with life. This sequence pertains to exposures to chemicals such as
cyanide, solvents, pesticides and any other chemical capable of entering
the body.
"Sensitivity
to a chemical results when the previous exposures to that chemical,
and/or other xenobiotics, have caused sufficient cumulative injury that
the excess functional capacity has been eroded away. At this point,
a chemical exposure that appeared to be well tolerated previously is
no longer tolerated, and is now encroaching on vital capacity.
"It
is a common observation that individuals who become sensitive to one
chemical often begin to react to others. This is because the body has
a limited number of detoxification mechanisms.
"When the mechanism has been damaged, all chemicals that are eliminated
through that mechanism will not be well handled and will provoke symptoms.
Individuals vary greatly in their abilities to resist the damaging effects
of chemicals. It is always the individuals with the least capacity to
tolerate chemicals who are the first to become sick. Others in the group
might tolerate the same chemical exposure indefinitely without apparent
illness.
"Nobody in the world today is free from some degree of chemical
body burden. Individual tolerances and exposures may vary greatly, but
we are all somewhere on the spectrum between minimal burden and having
taken on that last bit of chemical that pushes us over the brink into
a state of chronic illness." |